loading page

Management of new onset anosmia during the COVID pandemic - BRS Consensus Guidelines
  • +16
  • Claire Hopkins,
  • Mikkel Alanin,
  • Carl Philpott,
  • Philip Harries,
  • Katherine Whitcroft,
  • Ali Qureishi,
  • Shahram Anari,
  • Yujay Ramakrishnan,
  • Anshul Sama,
  • Elgan Davies,
  • Benjamin Stew,
  • Simon Gane,
  • Sean Carrie,
  • Iain Hathorn,
  • Raj Bhalla,
  • Christine Kelly,
  • Nina Hill,
  • Duncan Boak,
  • B. Nirmal Kumar
Claire Hopkins
Guy's Hospital

Corresponding Author:[email protected]

Author Profile
Mikkel Alanin
Guy's and Saint Thomas' Hospitals NHS Trust
Author Profile
Carl Philpott
University of East Anglia, University of East Anglia
Author Profile
Philip Harries
University Hospital Southampton NHS Foundation Trust
Author Profile
Katherine Whitcroft
South Yorkshire Deanery
Author Profile
Ali Qureishi
Oxford University Hospitals NHS Foundation Trust
Author Profile
Shahram Anari
University Hospitals Birmingham NHS Foundation Trust
Author Profile
Yujay Ramakrishnan
Nottingham University Hospitals NHS Trust
Author Profile
Anshul Sama
Nottingham University Hospitals NHS Trust
Author Profile
Elgan Davies
Spire Regency Hospital, Macclesfield
Author Profile
Benjamin Stew
University Hospital of Wales Healthcare NHS Trust
Author Profile
Simon Gane
Royal National Throat Nose and Ear Hospital
Author Profile
Sean Carrie
The Freeman Hospital and University of Newcastle
Author Profile
Iain Hathorn
University of Edinburgh
Author Profile
Raj Bhalla
Central Manchester & Manchester Children's Foundation Trust
Author Profile
Christine Kelly
Author Profile
Nina Hill
Fifth Sense
Author Profile
Duncan Boak
Fifth Sense
Author Profile
B. Nirmal Kumar
Author Profile


Objectives The primary aim of the study is to provide recommendations for the investigation and management of patients with new onset anosmia during the COVID-19 pandemic Design After undertaking a literature review, we used the RAND/UCLA methodology with a multi-step process to reach consensus about treatment options, onward referral imaging. Setting and participants An expert panel consistent of 15 members was assembled. A literature review was undertaken prior to the study and evidence was summarised for the panellists. Main outcome measures The panel undertook a process of ranking and classifying appropriateness of different investigations and treatment options for new onset anosmia during the COVID-19 pandemic. Using a 9-point Likert scale, panellists scored whether a treatment was: Not recommended, optional, or recommended. Consensus was achieved when more than 70% of responses fell into the category defined by the mean. Results Consensus was reached on the majority of statements after 2 rounds of ranking. Disagreement meant no recommendation was made regarding one treatment, using Vitamin A Drops. Alpha lipoic acid was not recommended, olfactory training was recommended for all patients with persistent anosmia of more than 2 weeks duration, and oral steroids, steroid rinses and omega 3 supplements may be considered on an individual basis. Recommendations have been made regarding the need for referral and investigation have been made. Conclusion This study identified the appropriateness of olfactory training, different medical treatment options, referral guidelines and imaging for patients with COVID-19 related anosmia. The guideline may evolve as our experience of COVID-19 develops.
21 May 2020Submitted to Clinical Otolaryngology
22 May 2020Submission Checks Completed
22 May 2020Assigned to Editor
01 Jun 2020Review(s) Completed, Editorial Evaluation Pending
05 Jun 2020Reviewer(s) Assigned
10 Jul 2020Editorial Decision: Revise Major
14 Jul 20201st Revision Received
15 Jul 2020Submission Checks Completed
15 Jul 2020Assigned to Editor
16 Jul 2020Reviewer(s) Assigned
26 Jul 2020Review(s) Completed, Editorial Evaluation Pending
17 Aug 2020Editorial Decision: Accept