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Analysis of 3.0 T1H-MRS Image Characteristics of Nasal Polyps
  • Li Yi,
  • Li Xuan
Li Yi
The 988rd Hospital of PLA

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Li Xuan
The 988rd Hospital of PLA.
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Abstract Background: Nasal polyp is a common disease in otorhinolaryngology, and its clinical diagnosis often needs pathological examination. At present, 3.0T1H-MRS can analyze the spectrum of brain glioma and other diseases, get biochemical metabolism information with clinical diagnosis value, and correctly diagnose brain glioma. Therefore, we use 3.0T1H-MRS to analyze the spectrum of nasal mucosa polyp, in order to make a clear diagnosis of nasal mucosa polyp through 3.0T1H-MRS. Objective: To analyze and study the 3.0T1H-MRS characteristics of nasal polyps, and to explore the value of 3.0T1H-MRS in the diagnosis of nasal polyps. Methods: 50 patients with nasal polyps from January 2010 to June 2019 were randomly selected from our department for study. All patients were pathologically verified and 3.0T was performed MRI, 3.0T1H-MRS focus detection, and quantitative analysis were compared with the normal brain tissue in the same side of the forehead. The main study was acetic acid (Ace), lactic acid (Lac), n-acetylaspartic acid (NAA), choline (Cho), creatine (Cr) peak integral value and the ratio of each integral value: Cho / NAA, Cr / Lac, Cr / NAA, Cho / Cr,Lac / NAA and Lac / Ace. Results:The expression of 3.0T1H-MRS in nasal polyps was significantly different from that in normal brain tissues: NAA decreased, Cho increased,Lac increased, Ace increased and most obvious; Lac / NAA ratio increased; Cho / NAA ratio increased and more obvious; Lac / Ace ratio decreased and most obvious; The difference between the two groups was statistically significant (P < 0.05). Conclusions: The analysis of 3.0T1H-MRS can get the biochemical metabolism information of clinical value: Ace(11.43 ± 6.11), NAA (17.76 ± 6.20), Cho (23.19 ± 6.91), Lac (12.51 ± 3.42), Lac / Ace (1.09 ± 0.56); Cho / NAA (1.34 ± 1.10), Lac / NAA (0.70 ± 0.55). According to the different integral values of acetic acid, lactic acid, n-acetylaspartic acid, choline and creatine, it is helpful for the correct diagnosis of nasal mucosa polyp.