Study on perinatal related factors of maternity and newborn in
parturients with intrapartum fever: a retrospective study
Abstract
Objective To investigate the impact of intrapartum fever on maternity
and fetus. Design Retrospective cohort study. Setting Women’s Hospital
of Nanjing Medical University, Nanjing, Jiangsu Province, China
Population We studied intrapartum fever, as well as non-fever
parturients, between January 1, 2018 and December 31, 2018. Methods We
collected pregnancy outcomes of intrapartum fever and non-fever mother
and neonatal data. Main outcomes and measures The obstetrics outcomes,
complete blood cell count (CBC) and thereby converted neutrophil to
lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and monocyte
to lymphocyte ratio (MLR), as well as vaginal secretion were observed in
women with and without intrapartum fever. Results Prepartum white blood
cell (WBC), red blood cell (RBC), and hemoglobin (Hb) were all higher in
febrile group, and WBC still higher but RBC and Hb lower after birth.
Postpartum NLR and MLR were all higher in fever group but not preferred
overtly difference before delivery. Additionally, the comparison of WBC,
RBC, Hb, platelets (PLT), neutrophils, and monocytes in prepartum and
postpartum all showed significant difference. Conclusions The
differences of the prepartum WBC, RBC, Hb, and monocytes existed in the
intrapartum fever and afebrile groups. Besides, the parturition could
bring about the change of the value of CBC and intrapartum fever might
aggravate or alleviate this change. Additionally, the intrapartum fever
might not be caused mainly by infection and the difference between
bacteria and fungus could reflect in the CBC. Keywords: Intrapartum
fever, perinatal period, vaginal discharge examination