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Improvement of Depression in a Patient with Hypothyroidism and Deiodinase Polymorphism with LT3 Therapy
  • +2
  • Ziyan Ahmed,
  • Rinsha Sherin,
  • Thanh Hoang,
  • Tatiana Fonseca,
  • Mohamed Shakir
Ziyan Ahmed
Walter Reed National Military Medical Center
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Rinsha Sherin
Walter Reed National Military Medical Center
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Thanh Hoang
Walter Reed National Military Medical Center
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Tatiana Fonseca
University of Chicago Andy Minn Oncology Lab
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Mohamed Shakir
Walter Reed National Military Medical Center
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Abstract

We report a 54-year-old man with treatment-resistant depression (TRD) and hypothyroidism who responded to LT3/LT4 combination, rather than LT4 alone. He was able to discontinue all antidepressant medications eventually. Interestingly, the patient has a DIO2 polymorphism.

Peer review status:UNDER REVIEW

31 Aug 2021Submitted to Clinical Case Reports
01 Sep 2021Assigned to Editor
01 Sep 2021Submission Checks Completed
24 Sep 2021Reviewer(s) Assigned
19 Oct 2021Review(s) Completed, Editorial Evaluation Pending