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Preliminary study on left bundle branch area pacing in children:clinical observation of 12 cases
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  • Wenlong Dai,
  • Baojing Guo,
  • Chen Cheng Dai,
  • Jian zeng Dong
Wenlong Dai
Capital Medical University Affiliated Anzhen Hospital

Corresponding Author:[email protected]

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Baojing Guo
Capital Medical University Affiliated Anzhen Hospital
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Chen Cheng Dai
Capital Medical University Affiliated Anzhen Hospital
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Jian zeng Dong
Capital Medical University Affiliated Anzhen Hospital
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Abstract

Objective: To explore the safety and feasibility of left bundle branch area pacing (LBBAP) in children. Methods: This study observed 12 children attempted LBBAP from 2019 to 2021 in our department prospectively. Clinical data, pacing parameters, electrocardiograms, echocardiographic measurements and complications were recorded at implant and during follow-up. Results: The 12 patients aged between 3 and 14ys and weighted from 13 to 48kg. 11 patients were diagnosed with third-degree AVB and 1 patient (case 4) suffered from cardiac dysfunction due to right ventricular apical pacing (RVAP). LBBAP was successfully achieved in all patients with narrow QRS complexes. LVEF of case 4 recovered on the 3rd day after LBBAP. The median of LVEDD Z score of the 12 patients decreased from 1.75 to1.05 3 months after implantation (p<0.05). The median of paced QRS duration was 103ms. The median of pacing threshold, R-wave amplitude and impedance were 0.85V, 15mV and 717Ω respectively and remained stable during follow-up. No complications such as loss of capture, lead dislodgement or septal perforation occurred. Conclusions: LBBAP can be performed safely in children with narrow QRS duration and stable pacing parameters. Cardiac dysfunction caused by long-term RVAP can be corrected by LBBAP quickly.
09 Sep 2021Submitted to Journal of Cardiovascular Electrophysiology
15 Nov 2021Submission Checks Completed
15 Nov 2021Assigned to Editor
16 Nov 2021Reviewer(s) Assigned
25 Jan 2022Review(s) Completed, Editorial Evaluation Pending
29 Jan 2022Editorial Decision: Revise Minor
06 Feb 20221st Revision Received
10 Feb 2022Assigned to Editor
10 Feb 2022Submission Checks Completed
10 Feb 2022Reviewer(s) Assigned
02 Mar 2022Review(s) Completed, Editorial Evaluation Pending
04 Mar 2022Editorial Decision: Revise Minor
18 Mar 20222nd Revision Received
24 Mar 2022Submission Checks Completed
24 Mar 2022Assigned to Editor
24 Mar 2022Reviewer(s) Assigned
01 Apr 2022Review(s) Completed, Editorial Evaluation Pending
03 Apr 2022Editorial Decision: Accept