Abstract
Rapid-onset hyponatremia as well as rhabdomyolysis are rare, but
potential, complications of olanzapine treatment. Hyponatremia,
secondary to atypical antipsychotic use, has been reported in many case
reports and is thought to be associated with a syndrome of inappropriate
anti-diuretic hormone secretion (SIADH). We report a case of
sudden-onset hyponatremia associated to a sever rhabdomyolysis resulting
in a coma necessitating intensive care unit admission. His evolution was
favorable after correction of all his metabolic disorders and Olanzapine
suspension.