Peste des petits ruminants (PPR) is an acute, highly contagious, world organization for animal health (OIE) notifiable and economically important transboundary viral disease of sheep and goats and caused by PPR virus (PPRV), which belongs to the genus Morbillivirus of the family Paramyxoviridae. The disease is endemic across Asia, the Middle East and African regions and is considered to be a major obstacle to the development of sustainable agriculture across the developing world due to huge burden for the economy and development of the affected countries and has recently been targeted by the OIE and the Food and Agriculture Organization (FAO) for eradication with the aim of global elimination of the disease by 2030. In this review, the regional epidemiology of PPR outbreaks and associated risk factors with special reference to the PPR-affected countries in South， Central and East Asia is comprehensively discussed.