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Electrogram-based AF ablation --finally, reproducibility!
  • Isabel Deisenhofer
Isabel Deisenhofer
German Heart Center Munich, Technical University of Munich (TUM)
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Abstract: After several years with sobering experiences with electrogram-based AF ablation approaches, Seitz et al present with the VX1 software a reliable tool to map and ablate spatio-temporal dispersion. The presented multicenter study in persistent AF patients was conducted in 1 expert and 7 satellite centers with a total of 17 operators, using the VX1 software to detect and subsequently ablate spatiotemporal dispersion. While the AF termination rate (88%) and the freedom from AF in 12 months FU (82%) was very encouraging, the VX1 software, using AI enhanced electrogram adjudication, achieved very similar results in all centers, regardless of the centre’s or the operator’s experience. Thus, the biggest criticism of electrogram-based ablation strategies, i.e. the lack of reproducibility in “non-expert” centers, seems to be finally addressed.
24 Jul 2022Submitted to Journal of Cardiovascular Electrophysiology
01 Aug 2022Assigned to Editor
01 Aug 2022Submission Checks Completed
01 Aug 2022Editorial Decision: Accept
21 Aug 2022Published in Journal of Cardiovascular Electrophysiology. 10.1111/jce.15660