Emergence of a Novel Reassortant H5N6 Highly Pathogenic Avian Influenza
Virus of Clade 2.3.2.1c from domestic poultry in China
Abstract
H5N6 avian influenza virus (AIV) has posed a threat to poultry and human
health. Here, we isolated a new clade 2.3.2.1 H5N6 virus, not like most
reported H5N6 AIVs of clade 2.3.4.4. Our analysis revealed a complex
pattern of its evolution in which the virus was derived as a result of
genetic reassortment among clade 2.3.2.1 and clade 2.3.4.4 H5 and H6N6
AIVs. Moreover, the results suggested that H5N6 clade 2.3.2.1 AIVs had
multiple reassortment pattern. It is necessary that to strengthen
continuing surveillance to prevent infection in human and poultry.