Objectives: Xerostomia is defined as the subjective feeling of dry mouth. It is a condition that affects millions of patients worldwide. The aim was to study prevalence and severity of self-reported xerostomia by sociodemographic variables and to evaluate self-reported halitosis, burning mouth, and mouth sores. Methods: A questionnaire regarding sociodemographic data and the 11-item Xerostomia Inventory was delivered to patients, 20-65 years of age applied to the XXXX University Faculty of Dentistry for dental treatment before the COVID-19 pandemic. Statistical analyses were performed to determine the relationships between the presence of xerostomia and other variables such as age, gender, the presence of a systemic disease, medication use, smoking, alcohol consumption, and the use of removable prostheses. Results: A total of 300 patients were included in the study; a prevalence of xerostomia of 54.6% was identified. A significant relationship was found between age and xerostomia ( p = 0.023; p = 0.001). The prevalence of xerostomia decreased as age increased. Xerostomia was more common in female patients ( p = 0.028; p = 0.004). The prevalence of xerostomia was found to be high, not only in the elderly, but also in younger adults. Conclusion: Xerostomia was reported in approximately one in two patients in an adult Turkish population. Factors associated with xerostomia were age, female gender and the number of cigarettes smoked per day. In this study, the high prevalence of xerostomia was due to smoking.