The authors show that (1) the RNL NRG1 is required for HopQ1-mediated cell death in N. benthamiana and that NRG1 silencing in N. benthamiana compromises the resistance to DC3000. They also show evidence that (2) expression of NRG1 within the normally susceptible plant Arabidopsis thaliana is sufficient to confer HopQ1-triggered cell death, as well as confer resistance to DC3000. In addition, the authors present evidence that (3) NRG1 is induced at an early time-point following PTI activation and hypothesize that this represents a link between PTI and ETI.