Figure 5. Annual cycle of Dromiciops gliroides showing its physiological, tissue, and biochemical changes during torpor and activity periods. Particular cellular alterations involve oxidative homeostasis by increasing molecular and enzymatic scavengers in torpor to inactivate reactive oxygen species generated during the activity period. The stages of the cycle were modified from Muñoz-Pedreros et al. (2005), according to a field experiment (Nespolo, Fontúrbel, et al., 2021).