Contribution to authorship
LA, FT and ABM contributed to the design of this study. LA, ALT, CCC, OP
included most of the patients. LA, LM, CR and FT conducted the analyses
and LA, LM, ABM, ALT, CCC, OP, CR and FT contributed to the
interpretation of data. LA, LM and FT drafted the manuscript and all the
authors critically revised the manuscript and approved the version to
published.
Trial Registration : EPIC trial. ClinicalTrials.gov number,
NCT00632567
This study (N° ID-RCB 2006-A00518-43) was approved by the Comité de
Protection des Personnes (Ethical Human Subjects Protection Review)
Paris-Ile-de-France V of Saint Antoine Hospital PARIS 12 on the 02
October 2007 (n°07709) and French Health Authority on 22 October 2007
(Ref: DGS2007-0188).