Current Knowledge
Physiology based mathematical models could be used to teach cardiorespiratory physiology and ventilation or determine optimal ventilation management.
SimulResp has been developed for modelling the children cardiorespiratory system, as none has been designed for this purpose so far.
What This Paper Contributes To Our Knowledge
SimulResp is able to produce blood gas values within the normal range when predicting blood gas values of healthy child over 8 years old spontaneously breathing or under mechanical ventilation.
Inconsistencies remain regarding prediction of blood gas values of healthy child under 8 years old or ventilated for pulmonary issues regardless of age.