Second phase of the study
The second phase intends to evaluate the quality of SimulResp when simulating blood gas values for real healthy or ill subjects in specific situations. We replicated, previously described in scientific literature, blood gas values in SimulResp. We used data from healthy men during physical activity (10) and immersed prone at 4.7 absolute atmosphere (ATA) (11), to evaluate SimulResp’s in spontaneously breathing subjects and data from a previously published study performed with ventilated pediatric intensive care subjects to evaluate SimulResp’s predictions in mechanically ventilated subjects (12).