Statistics
Differences between groups were determined using the unpaired
non-parametric Mann-Whitney test. IN-COL samples at the point of colitis
were compared with IN-COL at baseline, IN-NAE on 7-10 weeks treatment
were compared with IN-NAE at baseline, and UC flare was compared with
healthy volunteers and IN-COL patients a the point of colitis.
Categorical data were compared by the non-parametric chi-squared test.
Correlation analysis was performed using the non-parametric Spearman’s
test. All were performed using SPSS software (IBM, NY, USA). Medians and
interquartile ranges are reported throughout. A p value<0.05
was considered statistically significant, where multiple comparisons
were performed a Bonferroni correction was made as detailed in
individual figure legends.