Authors’ contributions
SCS conceived the study, designed and performed experimental work,
analysed the data, completed the literature review and wrote the
manuscript. JJZ designed experimental work provided expertise and
supervision in flow cytometry and critically reviewed the manuscript. KN
reviewed and collated clinical data and facilitated retrieval of stored
specimens. CMLM performed experimental work. BPF cared for patients,
oversaw translational research and collated clinical data. SD
facilitated archiving of clinical samples. AOB cared for patients and
oversaw translational research. CJ facilitated archiving and retrieval
of clinical samples. SAR facilitated archiving and retrieval of clinical
samples.GA cared for patients and oversaw translational research. UP
supervised translational research. RAS is the Director of the Melanoma
Institute Australia Biobank and provided critical review of the
manuscript. MSC conceived and facilitated the collaboration between
multiple sites and assisted in study design. MJP cared for patients and
oversaw clinical recruitment. VTFC cared for patients, facilitated
translational research studies and collated clinical data. TG
facilitated translational research studies. PK facilitated
collaborations between groups, supervised translational research and
critically reviewed the manuscript. GVL cared for patients, supervised
translational research and provided critical review of the manuscript.
OB cared for patients and is the lead investigator of the
gastrointestinal tissue studies. AMM cared for patients, designed the
study, supervised translational research and wrote the manuscript. ADK
designed the study, funded the experimental work, provided
infrastructural support and provided critical review of the manuscript.
All authors reviewed and approved the final manuscript.