Interpretation
Although two studies compared DP and SP for
MIP34,
40, the number of participants was
small, which might weaken the conclusions and leaded to the low quality
of evidence41. This
study had shown IPT-DP-4w was associated with lower risk of malaria
during pregnancy, moderate-to-high grade pigment deposition and
improvements in birth outcomes19. Therefore, in the
subgroup analysis, we divided the IPT-DP into two categories,
IPT-DP-4-6w and IPT-DP-8w to get substantially more precise summary
results.