Risk of bias in individual studies
Two authors (Xiajing Chu, Jingwen Li) independently assessed the risk of
bias using the Cochrane Collaboration’s
tool17. When
disagreements arose, a third investigator was consulted (Meixuan Li).
Each study was determined as having a low, high, or unclear risk of bias
relating to sequence generation, allocation concealment, blinding of
outcome assessors, incomplete outcome data, selective outcome reporting,
and other sources of bias. Any disagreements were resolved via
discussion among the
authors18.