Population
Between March 2017 and April 2019, a prospective cohort was created of consecutive singleton pregnancies complicated by early-onset severe PE who were admitted to the Departments of Maternal-Fetal Medicine at BCNatal (Hospital Clínic and Hospital Sant Joan de Déu, Barcelona, Spain). Additional inclusion criteria were the absence of maternal or fetal complications at admission immediate delivery.
The study protocol was approved by the Ethics Committee (HCB/2017/0077) and participants provided their written informed consent.