Figure 6
The effect of cladribine
on the mRNA expression of arginase 1 and iNOS in LPS-stimulated
microglia
mRNA expression of arginase 1 (Arg1) and iNOS was quantified by qPCR
after microglia were treated with DMSO (28.2 mM), LPS (10 ng/ml), DMSO
and LPS, and different concentrations of CdA (0.01-10 µM) together with
LPS for 24 hours. The expression is shown relative to DMSO control.
**p≤0.01, ***p≤ 0.001, n=4 in each group, one-way ANOVA followed by
multiple comparisons tests, mean±SD.