Aytug K. Kiper1,§, Sarah
Stalke1,§, Stefanie Marzian1,§,
Mauricio Bedoya2,3,§, David
Ramírez4, Alicia de la Cruz5,6,
Diego A. Peraza5,6, José C.E. Márquez
Montesinos2, Bárbara A. Arévalo
Ramos2, Susanne Rinné1, Teresa
Gonzalez5,6,7, Carmen
Valenzuela5,6,*, Wendy Gonzalez2,3,*
and Niels Decher1,*
1Institute for Physiology and Pathophysiology,
University of Marburg, Marburg, Germany.
2Centro de Bioinformática y Simulación Molecular,
Universidad de Talca, Talca, Chile.
3Millennium Nucleus of Ion Channels-Associated
Diseases (MiNICAD), Universidad de Talca, Talca, Chile.
4Instituto de Ciencias Biomédicas, Universidad
Autónoma de Chile, Santiago, Chile.
5Instituto de Investigaciones Biomédicas Alberto Sols
(CSIC-UAM), Madrid, Spain.
6Spanish Network for Biomedical Research in
Cardiovascular Research (CIBERCV), Instituto de Salud Carlos III,
Madrid, Spain.
7Biochemistry Department, School of Medicine,
Universidad Autónoma de Madrid, Madrid, Spain.
§Kiper AK, Stalke S, Marzian S and Bedoya M are joint
first author.
*Valenzuela C, Gonzalez W and Decher N are corresponding authors.
Running title: Essential binding site for local anesthetics in the Kv
‘side pockets´
Prof. Dr. Niels Decher
Institute for Physiology and Pathophysiology
Philipps-University Marburg
Deutschhausstraße 2
35037 Marburg, Germany
T: + 49-6421-28-62148
decher@staff.uni-marburg.de
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