Introduction
According to the World Health Organization (WHO) coronavirus disease
2019 (Covid-19) as a public health emergency is an international
concern1, First identified in Wuhan, China, it can
spread rapidly with a wide spectrum of severity 2.
There are various clinical features in COVID-19, ranging from
asymptomatic state to multi organ dysfunction and acute respiratory
distress syndrome 3. The typical symptoms include
cough, fever, headache, sore throat, myalgia, fatigue, breathlessness,
and conjunctivitis in some cases4 . Thus, it is hardly
distinguishable from other respiratory infections. By the end of the
first week, COVID-19 can lead to pneumonia, respiratory failure, and
death 5. About 66.6% of the patients had cough, but
only 44.7% of whom had a fever. Also, the sputum production was
observed in one-third of patients and sore throat was found in 14.0%,
Less than 5% of patients had gastrointestinal symptoms, such as nausea,
diarrhea, and vomiting 4. Fever and cough were the
most common symptoms among patients with pneumonia caused by COVID-196.In one of the first reports on the disease, Huang et
al. showed that the patients had dry cough, fever, dyspnea and malaise7.A suspect case is defined as a person with symptoms
including cough sore throat and fever, who had travelled to China or
other areas of local persistent transmission and had physical contacts
with confirmed COVID-19 infection patients6. The cases
may be asymptomatic or even without fever 8,9. A
confirmed case is a suspect case with a positive molecular
test8. Nonetheless, we visited two cases in Modarres
hospital clinic with naso-pharyngeal sputum who had no history of
sinusitis as the first symptom.
We presented two patients infected with COVID-19 were followed with
RT-PCR testing of throat swabs from Tehran, IRAN.