There is a vast number of biomaterials ranging from drug-eluting stents,
coated implants, drug delivery devices and artificial organs, among
others, that have been developed in recent years. However, translation
of many of these biomaterials to clinic is often plagued by
biocompatibility challenges. This review focuses on strategies
implemented in some of the recently developed biomaterials --
particularly for soft and hard tissue regeneration, organ manufacturing
and disease remediation -- to overcome potential foreign body response
to the incorporation of the biomaterials in the host.