5 CONCLUSIONS
In conclusion, the chitosan-PEG nanocomposite hydrogels loaded with phomopsidione were successfully synthesized and characterized. The characterization results have revealed that the nanocomposite hydrogels have great promise to act as antimicrobial dressings for chronic wounds. The testing of the nanocomposite hydrogel should be further extended toin vivo study to evaluate the efficacy with the animal models simulating the chronic pressure ulcers.