1 | INTRODUCTION
Uterine cervical cancer (UCC) is a common cancer that causes >311,000 deaths worldwide each year1. Advances in radiotherapy and chemotherapy have markedly improved the treatment outcomes of UCC 2. Translational research efforts have provided information on the biological properties of tumors associated with treatment responses in patients with UCC3–5, which may help to personalize treatment strategies.
Although UCC is a common cancer, a subset that produces granulocyte-colony stimulating factor (G-CSF) is rare. G-CSF-producing UCCs are highly aggressive6–13. However, specific patterns of care for G-CSF-producing UCCs have not been established, and treatment outcomes remain unknown because of the limited number of reported cases. Moreover, the mutation profile of G-CSF-producing UCC has not been analyzed. Here, we report a case of G-CSF-producing UCC, and the results of mutational analysis and literature review.