4 | CONCLUSIONS
We reported a case of G-CSF-producing UCC that showed rapid disease
progression after definitive chemoradiotherapy leading to an overall
survival period of 5 months. The aggressive behavior of this tumor
against conventional treatment was in line with the findings described
in previous reports on G-CSF-producing UCCs. This study is the first
report describing the somatic mutation profile of G-CSF-producing UCC.
The data presented will expand our biological understanding of this
cancer subset, which warrants further investigation.