Angiotensin Converting Enzyme 2 (ACE2)
ACE2 is one of the key receptors for SARS-CoV invasion of the human body
[32]. Researchers found that SARS-CoV-infected or recombinant
wild-type SARS-spike protein-treated mice displayed significantly
reduced ACE2 expression in the lung. It has also been shown that the
latest outbreak of coronavirus pneumonia (2019-nCoV, SARS-CoV-2) is
invading human alveolar epithelial cells and is therefore, could be
screened against 2019-nCoV, suggesting further studies [33]. Since
ACE2 is abundantly present in human epithelia of the lung and small
intestine, may influence the type of therapeutics against 2019-nCoV.