loading page

Establishing UK Research Priorities In Smell and Taste Disorders: A James Lind Alliance Priority Setting Partnership
  • +7
  • Carl Philpott,
  • Andreas Espehana,
  • Mairenn Garden ,
  • Ngan Ta,
  • Nishita Gadi,
  • Kala Kumaresan ,
  • Devina Maru,
  • Lorenzo Dante Stafford,
  • Nina Bleasdale,
  • Duncan Boak
Carl Philpott
University of East Anglia

Corresponding Author:[email protected]

Author Profile
Andreas Espehana
University of East Anglia Faculty of Medicine and Health Sciences
Author Profile
Mairenn Garden
University of East Anglia Faculty of Medicine and Health Sciences
Author Profile
Ngan Ta
Norfolk and Norwich University Hospitals NHS Foundation Trust
Author Profile
Nishita Gadi
Anglia Ruskin University
Author Profile
Kala Kumaresan
University of East Anglia Norwich Medical School
Author Profile
Devina Maru
Royal College of General Practitioners
Author Profile
Lorenzo Dante Stafford
University of Portsmouth Department of Psychology
Author Profile
Nina Bleasdale
Fifth Sense
Author Profile
Duncan Boak
Fifth Sense
Author Profile


Background: A James Lind Alliance Priority Setting Partnership (JLAPSP) was established by Fifth Sense together with UEA to identify the top 10 research questions in the field of smell and taste disorders in the United Kingdom. Methods: After steering group was established, an electronic survey was disseminated to all stakeholders (patients, healthcare professionals, family, carers, researchers) to determine the list of questions. After removing out-of-scope responses, the remainder were consolidated to create summary questions. A literature search was conducted to remove already answered questions. A second survey was used to determine the top questions that formed the subject of final debate at a workshop attended by clinicians and patients to determine the top 10 priorities. Results: The 665 respondents to the initial survey provided 1698 research questions. Thirteen were out-of-scope and removed; remaining 1685 were then consolidated to form 147 summary questions. Following literature search and discussion with the steering group, 37 questions remained for the second survey, which 235 people responded. The top ten priorities agreed in the workshop covered themes of improved understanding of pathophysiologlogy, improving health services, and managing long-term effects of smell/taste disorders. The most important research question agreed was “How can we further our understanding of the mechanism of disease in the nerve pathways that affect smell and taste disorders, including where parosmia and phantosmia exist.” Conclusions: We report the top 10 research priorities in smell and taste disorders. These priorities will now empower researchers to secure research funding and provide the basis of the Fifth Sense research hub.
30 Mar 2022Submitted to Clinical Otolaryngology
19 Apr 2022Submission Checks Completed
19 Apr 2022Assigned to Editor
09 May 2022Reviewer(s) Assigned
27 May 2022Review(s) Completed, Editorial Evaluation Pending
26 Jun 2022Editorial Decision: Revise Minor
06 Jul 20221st Revision Received
14 Jul 2022Submission Checks Completed
14 Jul 2022Assigned to Editor
25 Jul 2022Reviewer(s) Assigned
15 Aug 2022Review(s) Completed, Editorial Evaluation Pending
10 Sep 2022Editorial Decision: Accept
Jan 2023Published in Clinical Otolaryngology volume 48 issue 1 on pages 17-24. 10.1111/coa.13985