Name Original use Antiviral mechanism Result Reference
Drugs reported effective Remdesivir Broad-spectrum RNA virus antiviral drug (SARS/MERS/Ebola) Pre-terminate the RNA chains of the virus before mature Infecting cells: EC50=0·77μM, EC90=1·76μM. Involving one treatment in America and France respectively, both patients had been cured. (Dealmoon, 2020; Holshue et al., 2020; M. Wang et al., 2020)
Chloroquine Treats Malarial and autoimmune disease Escalating the endosomal PH to inhibit cell fusion Infecting cells: EC50=6·90μM, EC90=1·13μM. 100 cases of patient treated, considerable effect had shown and no adverse reaction was reported. (M. Wang et al., 2020; YSA, 2020)
Hydroxychloroquine Treats Systemic lupus erythematosus Escalating the endosomal PH to inhibit cell fusion 20 cases of patients treated, significant improvement in 19 cases (Publish, 2020)
Favipiravir Anti-Influenza Inhibits the RNA-dependent RNA polymerase of RNA viruses Infecting cells: EC50=61·88μM. Further evaluation of SARS-CoV-2 had been conducted. (Clercq, 2020; M. Wang et al., 2020)
Arbidol Anti-Influenza Interferes the cell membrane’s fusion with the virus. Abidol at a concentration of 10 to 30 micromolar can effectively inhibit coronavirus up to 60 times compared with a drug-untreated control group (qi, 2020)
Darunavir Anti-HIV Prevents virus from using the ribosomes of the host cell to synthesize proteins needed by the virus (But its mechanism on against SARS-CoV-2 is still unknown) at a concentration of 300 micromolar, darunavir can significantly inhibit virus replication (qi, 2020)
Chinese Traditional Medicine  ··  ·· 214 confirmed cases had shown an over 90% rate of effective, of which the symptoms of 60% of patients experienced significant improvement, 30% of patients with stable symptoms without exacerbation (Ping;, 2020)