3.5 pCIgD-Man-L induces BoHV-1 specific proliferation of lymphocytes
Lymphoproliferation was evaluated at 12 dpc in PBMCs after in vitro stimulation with inactivated BoHV-1. The results showed that pCIgD-Man-L treated group underwent the highest degree of proliferation with respect pCIneo (p<0.01) and pCIgD group (p<0.05) (Fig. 5 ). This result indicates that liposomes possess a remarkable “adjuvant” effect and are capable of enhancing cellular immune response elicited by pCIgD in bovines.