Peak Trough Reference
B cells 0200 h – 0300h 1100 h (Born, Lange, Hansen, Molle & Fehm, 1997)
T cells: Naive, central memory, effector memory CD4+ and CD8+ T cells
0200 h
1400 h
(Dimitrov, Benedict, Heutling, Westermann, Born & Lange, 2009)
Effector CD8+ T cells 1400 h 0200 h (Dimitrov, Benedict, Heutling, Westermann, Born & Lange, 2009)
NK cells 1100 h – 1400 h 0200 h (Born, Lange, Hansen, Molle & Fehm, 1997)
IL-10* First peak 0730 h Second peak 1930 h (Young, Matthews, Kanabrocki, Sothern, Roitman-Johnson & Scheving, 1995)
IFNγ 0000 h to 0300 h 0800h to 1100 h (Petrovsky & Harrison, 1998; Petrovsky, McNair & Harrison, 1998)