Intervention
Information regarding the effect of MS was extracted from a recent
systematic review and meta-analysis included in the review mentioned
previously(8). This study included trials that evaluate the effect of MS
( 25-50 mg/kg through 20 min) in patients (range of age of 6-18 years)
with acute asthma moderate-severe. All children were treated initially
with inhaled albuterol (0.15 mg/kg) by facemask or mouthpiece from
nebulizer. On completion of this treatment and after of confirmation a
peak expiratory flow rate less than 60%, in all children were given a
second albuterol treatment, intravenous methylprednisolone, and
intravenous magnesium sulfate or placebo (normal saline solution)(17-19)
.