Focus Potential benefit(s)
Basic science
Immune response to SARS-CoV-2
Define immune pathways Define immune therapeutic targets Define antibody induction and duration
Redirection of new knowledge toward understanding and implementing immunotherapies for pediatric cancer
ACE2 receptor Explore role in lung metastases Increased understanding for tumor immunology
Endothelial cell activation COVID-19-related microangiopathy and thrombosis Increased understanding for vascular metastasis and thrombosis
Clinical research
Biorepository Collect samples prospectively, analyze retrospectively Define mechanism of action and biologic effects as new diagnostics and therapies advance
Repurposing cancer therapeutics
Data collection on cancer patients with and without COVID-19 Define influence of COVID-19 on cancer outcomes
Epidemiology studies SARS-CoV-2 and risk for childhood malignancies