Basic science |
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Immune response to SARS-CoV-2
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Define immune pathways
Define immune therapeutic targets
Define antibody induction and duration
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Redirection of new knowledge toward understanding and implementing
immunotherapies for pediatric cancer
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ACE2 receptor |
Explore role in lung metastases |
Increased
understanding for tumor immunology |
Endothelial cell activation |
COVID-19-related microangiopathy and
thrombosis |
Increased understanding for vascular metastasis and
thrombosis |
Clinical research |
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Biorepository |
Collect samples prospectively, analyze retrospectively |
Define mechanism of action and biologic effects as new diagnostics and
therapies advance |
Repurposing cancer therapeutics |
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Data collection on cancer patients with and without COVID-19 |
Define
influence of COVID-19 on cancer outcomes |
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Epidemiology studies |
SARS-CoV-2 and risk for childhood malignancies |
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