Results
Significantly fewer women with Marfan syndrome gave birth, compared to
the background population. In Marfan syndrome, complications related to
cervix were increased (HR: 19.8 (95% CI: 2.2-177.5)) and the number of
caesarean sections was higher (HR: 2.09 (95% CI: 1.41-3.08)). No women
with known Marfan syndrome had a pregnancy related aortic dissection and
the consequences of pregnancy and delivery on future aortic events
seemed limited. Among undiagnosed women with Marfan syndrome there were
more foetal deaths and all delivery-related dissections came from this
subgroup.