Results
In total, 91 out of the 195 Danish women with Marfan syndrome (47%) and 10,188 out of their 19,500 (52%) controls, had at least one registration related to “Maternal health” and thus a pregnancy (Table 1), corresponding to a significantly decreased hazard ratio (HR) of 0.79 (95% CI: 0.64-0.97). Seventy-four women with Marfan syndrome (out of the 91) gave birth to 142 children, and their 6,185 controls gave birth to 12,088 children.
Fifty women with Marfan syndrome (55 %) were not diagnosed with Marfan syndrome at the time of their first registration related to “Maternal health” and 40 of these had one or more registrations of delivery and thus gave birth to one or more children.