3.2 Tumor Necrosis
Median tumor necrosis was 94% (range, 5%-100%). In the whole cohort,
100% TN was seen in 43 patients (16.7%) 90-99% TN in 105 (40.7%) and
<90% TN in 110 patients (42.6%). Proportion of patients with
100%, 90%, 70% TN was comparable across whole cohort and localized
and metastatic groups (Supplemental TABLE S3). Proportion of patients
with 100%TN across whole cohort, localized and metastatic cohorts were
16.7%, 16.5% and 17.3% respectively. For ≥ 90% TN, the corresponding
figures for whole cohort, localized and metastatic cohorts were 57.4%,
55.8%, 63.5% respectively. Similar values for ≥ 70% TN were 85.3%,
84.5%, 88.5% respectively. Similar distribution of patients across the
different cut-offs were obtained on comparing with cohorts from the
various co-operative groups (Supplemental TABLE S2).