Acknowledgements
We warmly thank all study participants of Department of Biopharmacy in College of Life Sciences and Medicine, Zhejiang Sci-Tech University, who helped in the realization of this study. This work was funded by Public Welfare Technology Application Research Project of Zhejiang Province [No. 2017C32049]; Key Research and Development Program of Zhejiang Province [No. 2019C02043]; and the Science Foundation of Zhejiang Sci-Tech University [No. 16042062-Y].