3.3 BCG consensus gene signature
Our workflow starts with the prioritization of a gene signature to study
BCG’s network pharmacology. First, we derived a consensus gene signature
(CGS) for BCG based on GEO’s dataset GSE58636. Details on BCG-CGS
signature are found in table S1 (Supporting Information). Twenty-two
differentially-expressed genes across all 4 experiments (2 Groups x 2
time points discussed in Methods) formed BCG’s consensus gene signature
(BCG-CGS) shown in Figure 2A.