Systematic reviews of the evidence
Three key questions were addressed: (i) What are the challenges and
specific needs of adolescents and young adults with allergic conditions,
including asthma, food allergy and anaphylaxis, allergic
rhino-conjunctivitis, atopic dermatitis, chronic urticaria, allergic
gastrointestinal disease, as well as those with complex multisystem
allergic disease? (ii) What specific strategies have proven useful to
improve self-management and wellbeing in this population? (iii) What
generic approaches are helpful when managing adolescents and young
adults? The first two were pursued through two formal systematic reviews
(SRs) of the evidence with a cut-off date of February 10,
2019.7,8 The final question was assessed by a SR of
the evidence-based adolescent and young adult guidelines from the last 5
years with a cut-off date of June 21, 2019. Individual studies from
these guidelines were accessed to determine level of evidence and grade
of recommendation. The TF members continued to track evidence published
after our systematic review cut-off date and, where relevant, studies
were considered by the TF chairs.