What is the role of T regulatory cells in COVID-19 pathogenesis?
There are no longitudinal studies analyzing T regulatory cells in COVID-19. A limited number of studies have reported decreased numbers of circulating T regulatory cells (CD3+CD4+CD25+CD127low+) as a part of lymphopenia. Further studies are needed to explore their roles in COVID-19 pathogenesis as well as in controlling severe tissue injury or CSS.49,76