Corticosteroids inhibit rhinovirus and RSV-induced cytokine release in vitro. Do inhaled corticosteroids have a protective effect against SARS-CoV-2?
Recent evidence indicates that inhaled corticosteroid treatment reduces the expression of viral membrane receptors used to infect the human airways in a dose-dependent manner.131 On the other hand, the immune suppression exerted by corticosteroids may impair anti-viral responses.125 However, there are no clinical studies investigating the effect of inhaled corticosteroid on SARS-CoV-2 infection rates.