What is the impact of nonsteroidal anti-inflammatory drugs use in symptomatic COVID-19 patients?
Fang et al .178 suggested that there is ACE2 overexpression upon treatment with ACE inhibitors, thiazolidinediones and ibuprofen. There were concerns pertaining to the use of nonsteroidal anti-inflammatory drugs in COVID-19 patients. The European Medicines Agency clarified that no scientific evidence established a link between ibuprofen, or other nonsteroidal anti-inflammatory drugs, and a risk to worsen COVID-19.179