Drug Generic Name Chemical Structure Drug class Mechanism of Action Dosage and Mode of Administration Side Effects Clinical trials References
Remdesivir Remdesivir Inhibits Viral Synthesis Stopping genome replication by blocking the polymerase activity 6-12 vials to be administered for a Patient with severe attack Infusion related reaction (including hypotension, nausea, vomiting, diaphoresis, and shivering) 1000 Trials in Punjab started on 09-june-2020 (Services, 2020)
Clexan Enoxaprin Anticoagulant Accelerate the activity of antithrombin III, inhibition of coagulation factors 40mg once a Day in start of Covid-19, In severe attack 12 hourly Unusual bleeding, or any bleeding that will not stop, purple or red spots under your skin.
Xarelto Rivaroxaban Anticoagulant Inhibit free and clot bound factor Xa 10mg once a day Increases the risk of thrombotic events
Depo-Medrol Methyl-predinisolone Corticosteroid Decrease the inflammatory cycle 0-1mg/kg/day for 5 consecutive days. Black, Tarry Stools, Joint Pain, Limp, Blurred Vision, Joint Pain, Blindness. (C. Wu et al., 2020)
Stromectol Ivermectin Anti-parasite Inhibits the replication of SARS-CoV-2 600 ug/kg dose daily for 3 days Fever, pruritus, and skin rashes. Trials are done on Patients with mild to moderate attack of Covid-19. (Caly et al., 2020)
Azasite/ Z-max Azithromycin + Chloroquine Antibiotic/ additional immunodulatory effects Binds to the 23s of rRNA of the bacterial 50s Ribosomal unit. Stop Sbacterial protein synthesis 2 Tabs Hydoxychloroquine twice a day and 2 Tabs Azithromycin twice a Day. Diarrhea, loose stools, and nausea. 9 Patients were kept under trial, 4 in PKLI and 5 in other hospitals. (Yousufzai, 2020)
Acterma Tocilizumab C6428H9976N1720O2018S42 Interleukin-6 inhibitor Inhibits T-cells differentiation binds with membrane bound IL-6 receptors. 80 mg/4ml, 200 mg/10 ml for intravenous injection Sinus pain, mild stomach cramps, urinary tract infection (Malik, 2020)