Molecular imaging for thrombosis
Thrombosis is a complex event, usually a result of undesired and
uncontrolled platelet adhesion and aggregation, as well as increased
thrombin formation and fibrin generation, within a vessel (Ziegler et
al., 2019; Montague et al., 2020). Therefore, biomarkers of platelet
activation and fibrin generation have attracted major attention as
molecular targets for molecular imaging of arterial and venous
thrombosis. As microthrombosis plays an important role in
ischemic-reperfusion (I/R) injury, these targets have also been used to
image, for example cardiac I/R injury (Ziegler et al., 2019).