SNP selection and genotyping
For genotyping purposes, 20 SNPs derived from 17 genes were pinpointed. Detailed attributes of these SNPs, including their locations, presumed functions, along with the findings of MAF and HWE, are catalogued inTable 2 . Here, MAF is indicative of the frequency of the rarest allele among our study’s participants. Three SNPs - rs6787801 (LP2RY12), rs1045642 (ABCB1), and rs2307240 (CES1) - exhibited an MAF lower than 0.05. This discrepancy might arise due to the limited sample size. However, when consulting the HapMap database, all SNPs manifested MAFs exceeding 5%. Furthermore, the genotype distribution remained congruent with HWE (P > 0.05), signifying no noteworthy deviation for any SNP across the patient spectrum.