Recipient Age, mean (SD) |
54.1 (12.1) |
53.5
(12.4)) |
53.9 (12.3) |
0.05 |
Gender, female |
1528 (26.0%) |
1532 (26.3%) |
1527 (26.2%) |
0.96 |
Rejection Risk score, median (IQR) |
8 (6-9) |
8
(6-10) |
8 (6-9) |
<0.001 |
Induction therapy |
767 (13.1%) |
2697 (46.3%) |
5066 (86.9%) |
<0.001 |
Basiliximab |
452 (7.7%) |
1,120 (41.5%) |
3,314 (65.4%) |
|
Thymoglobulin |
256 (4.4%) |
1,151 (19.7%) |
1,360 (27%) |
|
Ethnicity |
|
|
|
<0.001 |
Caucasian |
3813 (65.0%) |
3819 (65.5%) |
3954 (67.8%) |
|
African American |
1240 (21.1%) |
1210 (20.8%) |
1283 (22.0%) |
|
Hispanic |
551 (9.4%) |
509 (8.7%) |
324
(5.6%) |
|
Body Mass Index (kg/m2) |
27.4 (4.9) |
27.1 (4.8) |
27.5 (5.1) |
<0.001 |
Diagnosis |
|
|
|
<0.001 |
Non-Ischemic Dilated Cardiomyopathy |
2987 (50.9%) |
3046 (52.3%) |
3056 (52.4%) |
|
Ischemic Cardiomyopathy |
2167 (36.9%) |
1989
(34.1%) |
2104 (36.1%) |
|
Congenital |
127 (2.2%) |
129 (2.2%) |
188 (3.2%) |
|
Restrictive Cardiomyopathy |
89 (1.5%) |
100
(1.7%) |
53 (0.9%) |
|
Hypertrophic Cardiomyopathy |
122 (2.1%) |
182
(3.1%) |
135 (2.3%) |
|
Valvular |
179 (3.1%) |
218 (3.7%) |
180
(3.1%) |
|
Status 1A |
3812 (65.0%) |
3716 (63.8%) |
3696 (63.4%) |
0.18 |
Class I PRA > 20% |
321 (5.5%) |
337 (5.8%) |
354 (6.1%) |
0.38 |
Class II PRA > 20% |
228 (3.9%) |
263 (4.5%) |
242 (4.2%) |
0.24 |
Diabetes Mellitus |
1726 (29.4%) |
1571 (27.0%) |
1647
(28.3%) |
0.01 |
Intra-Aortic Balloon Pump |
312 (5.3%) |
201
(3.4%) |
320 (5.5%) |
<0.001 |
Inotropes at listing |
1809 (30.8%) |
1969
(33.8%) |
2083 (35.7%) |
<0.001 |
Serum Creatinine in mg/dL, mean (SD) |
1.20 (.4) |
1.22(.4) |
1.24(.5) |
<0.001 |
Pre-Transplant Mechanical Ventilation |
36 (0.6%) |
82 (1.4%) |
83 (1.4%) |
<0.001 |
Transfusions While Listed |
1350 (23.0%) |
1301
(22.3%) |
1406 (24.1%) |
0.06 |
Pre-Transplant Dialysis |
52 (0.9%) |
59 (1.0%) |
39 (0.7%) |
0.13 |
Left Ventricular Assist Device Support |
1774 (30.2%) |
1305 (22.4%) |
1677 (28.8%) |
<0.001 |
Heartmate 2 |
1466 (25.0%) |
949 (16.3%) |
1246 (21.4%) |
|
Heartmate 3 |
69 (1.2%) |
43 (0.7%) |
51
(0.9%) |
|
HeartWare |
239 (4.1%) |
313 (5.4%) |
380
(6.5%) |
|
HLA mismatch (>3) |
4200 (71.6%) |
4761 (81.7%) |
4729 (81.1%) |
<0.001 |
Gender mismatch |
4359 (74.3%) |
4392 (75.3%) |
4531 (77.7%) |
<0.001 |
CMV match |
3062 (52.2%) |
3049 (52.3%) |
2957 (50.7%) |
0.17 |
Donor-to-Recipient Weight Ratio, mean (SD) |
1.01 (.24) |
1.03 (.24) |
1.01 (.23) |
<0.001 |