Material and methods
We recorded 53 COVID-19 cases in an isolated community (883 inhabitants in 2019) in the high disease prevalence Ciudad Real province, Spain, from the first case detected on March 3, 2020, to the last one on May 9, 2020. Case definition included bilateral pneumonia, often with loss of smell and taste (Wang et al., 2020; Huang et al., 2019). Fifty-three cases were classified as moderate, severe or very severe (score 1, 2 and 3, respectively) and duration of symptoms was recorded as another proxy for severity (Ding et al., 2020). SARS-CoV-2 was confirmed by RT-PCR in 22 patients. Cases were representative of the general population (mean case age, 54 years-old, 30 males, 23 females; mean population age, 49 years-old). Patients without bilateral pneumonia were excluded.
The data that support the findings of this study are available from the corresponding author upon reasonable request.