Conclusions
In summary, according to our study, patients with type-1 BrS had a low rate of life-threatening events. Proband status and spontaneous type 1 ECG in conventional leads were more common in the symptomatic group. Gender, family history of SCD, inducibility of ventricular tachyarrhythmias during EPS, and presence of a SCN5A variant were not predictors of symptoms. Patients with SCN5A-mediated BrS exhibited more conduction abnormalities. More studies are still necessary to better understand the gaps and to improve risk assessment in these challenging patients with Brugada Syndrome.