Variation of clinical and echocardiographic parameters with PALS
Individuals with a reduced PALS were significantly older (60.4 ± 11.1 vs 54.6 ± 11.9 years, p = 0.013), had a greater BMI (30.1 ± 6.0 vs 27,1 ± 4.4 kg/m2, p = 0.007), higher systolic blood pressure (SBP) (p = 0.034) and greater E/E’ ratio (12.1 ± 4.6 vs 8.9 ± 2.3, p < 0.001). Furthermore, LAVi (p = 0.006), LA expansion index (p < 0.001), LA global (p < 0.001) and active (p = 0.002) ejection fractions were significantly higher in subjects with abnormal PALS (Table II).
On multivariate analysis, E/E’ ratio (adjusted p = 0.032) and BMI (adjusted p = 0.022) were independently associated to abnormal PALS after adjustment for all the significant variables.