Comparing IgG4:IgE ratios between PA and PS groups
Comparison of peanut IgG4 and IgG4:IgE ratios between PA and PS children revealed significantly higher peanut-specific IgG4:IgE ratios in the PS group compared to the PA group at 36m of age (191.4 vs 19, p<0.01) and at the 7-11y time point (544 vs 11.3, p<0.001), respectively (Table 2). This was also reflected in the subgroup analysis, with the children who did not have PA because they outgrew it or never had it, as they had higher peanut-specific IgG4:IgE ratios compared to those who had persistent or new PA at both the 36m (p<0.05) and 7-11y (p<0.01) time points.