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Regression of CD30-Positive Large Cell Transformation Arising on Patch-Lesion of Early Mycosis Fungoides
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  • Naoko Kubo,
  • Munenari Itoh,
  • Yoshinori Watanabe,
  • Yoshimasa Nobeyama,
  • Akihiko Asahina
Naoko Kubo
Jikei University School of Medicine

Corresponding Author:[email protected]

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Munenari Itoh
Jikei University School of Medicine
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Yoshinori Watanabe
Jikei University School of Medicine
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Yoshimasa Nobeyama
The Jikei University School of Medicine
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Akihiko Asahina
Jikei University School of Medicine
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Abstract

We present the case of a patient with patch-stage mycosis fungoides who developed ulcerative tumors compatible with large cell transformation. Tumor cells were positive for CD30 and CXCR3 and negative for CCR3, and subsequently exhibited spontaneous regression. Thus, large cell transformation in early mycosis fungoides may not indicate poor prognosis.
20 Jun 2020Submitted to Clinical Case Reports
20 Jun 2020Submission Checks Completed
20 Jun 2020Assigned to Editor
26 Jun 2020Reviewer(s) Assigned
01 Jul 2020Review(s) Completed, Editorial Evaluation Pending
03 Jul 2020Editorial Decision: Accept
Dec 2020Published in Clinical Case Reports volume 8 issue 12 on pages 2418-2422. 10.1002/ccr3.3171