Data extraction
Data extraction was conducted independently by two investigators (WXQ
and JYC), and any discrepancy between the reviewers was resolved by
consensus. For each study, the following information was extracted:
study name, treatment setting, anti-HER2 regimen and dosage, duration of
anti-HER2 therapy, concomitant therapy, No. of LVEF decline, No. of CHF
and No. of patients for safety analysis.