2.2 Serum samples
This study used serum from 39 patients [median age 8 years (IQR 6–10 years)], from a previous study, with persistent CM allergy before oral immunotherapy.4,7 These patients were required to have retained their milk allergy over age 5 with the threshold dose less than 5 mL of CM confirmed by an oral food challenge test, and detectable specific IgE to CM and whole CN by ImmunoCAP®.