Data sources and searches
In the search strategy, we included randomized controlled trials (RCTs),
non-randomized controlled clinical trials, prospective and retrospective
comparative cohort studies, and case-control studies. Every study that
included women treated with statins during pregnancy was analysed.
Duplicated reports, case reports, case series, cross-sectional studies,
pharmacokinetic studies in healthy adults, animal studies, reviews,
expert opinion, editorials, letters to the editor, comments, and studies
with a high risk of bias were excluded.