Deterministic and probabilistic sensitivity
analyses
The utility values resulted in the highest change in the ICER (Figure
3). In all evaluated analyses the SCIT+ICS remained cost-effective.
Probabilistic sensitivity analyses indicated that SCIT+ICS was
cost-effective in 95.2% of iterations when compared to ICS and 88.7%
of iterations were associated to a gain in QALYs. The SCIT+ICS showed an
increasing probability of being cost effective as the WTP threshold
increased (See supplementary material 2).