Subcutaneous immunotherapy with either Salmeterol/Fluticasone or Formoterol/Budesonide. AA = allergic asthma, AR = allergic rhinitis, SCIT = subcutaneous immunotherapy, ICS = inhaled corticosteroids, LABA = long acting β2agonists, ED = emergency department, QALYs = quality-adjusted-life years, ICER = incremental cost-effectiveness ratio.