Anti-D concentration at delivery
At delivery, the variation of anti-D concentration was large, between
14.4 and 184 IU/L, with mean and SD of 60±34 IU/L, Fig 3. Median
gestational age of delivery was 40 weeks (38-42 weeks). Five women were
recommended additional prophylaxis due to a weak result in the type and
screen test at delivery. They had anti-D concentrations between 14.4 and
30 IU/L (3-6 µg/L). Two of the five women had levels below 15 IU/L (14,4
and 14,5). One of the women had high BMI, 34, and both had low
concentrations at all measurements. The other three women had
concentrations of 27-30 IU/L. In 25/39 FMH was analysed after delivery
and the results were negative in all, i.e. below the LOD, 1 mL fetal
blood in maternal circulation.
The women were monitored up to 30 days postpartum, showing stable
protective levels of anti-D after delivery, Fig. 3. The concentration of
anti-D analysed at delivery and in postdelivery samples (n=59) were
61+ 28 IU/L (mean+ SD) after administration of anti-D 1500
IU in gestational week 38+ 1, excluding the five women who got a
new dose anti-D at delivery.